Research

Investigation of the role of rfp-1 in synaptic signaling in C. elegans

Abstract Proper neuronal signaling is crucial for any organism to maintain its neurological functions. Abnormal changes in neurotransmitter levels are implicated in neuropsychiatric and neurodegenerative diseases. Deficiencies in the balance of excitatory and inhibitory neurotransmission occur in several types of neurodegenerative disease, and deficiencies in sensory signaling can accompany and exacerbate these conditions. A common …

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An Explorative Study Examining the Function of Physical Touch in the Lives of Young Adults Before and After the Covid-19 Pandemic

Abstract Interaction and connection through physical touch is fundamental to the human experience. It is so elemental, in fact, that human beings often go through their daily lives without consciously thinking about touch and the critical role it plays in their lives. As the Covid-19 pandemic became increasingly more threatening, the existence of physical touch …

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Investigation of the Roles of fshr-1 and sphk-1 on Life History Traits in C. elegans

Abstract The later years of life are often characterized by declining cognitive function and mobility. One contributor is the cellular accumulation of reactive oxygen species (ROS). However, our understanding of how cells respond to ROS to promote health and survival is incomplete. We focused here on two genes, follicle stimulating hormone receptor-1 (fshr-1) and sphingosine …

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Effects of Binding Pocket Mutations on Substrate Specificity and Enzyme Efficiency of BS2 esterase

Introduction           Serine hydrolases are one of the largest groups of enzymes and the most commonly used for biocatalysts. They are identified by the presence of a highly nucleophilic serine residue within the catalytic triad or dyad that hydrolyze substrates (Kazlauskas). BS2 from bacteria Bacillus subtilis is one known serine hydrolase that has an unselective …

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Using NASA’s TESS Mission to Search for Extremely Low Mass White Dwarf Stars

Abstract Extremely low-mass white dwarf stars (ELM) are white dwarf stars with a mass lower than 0.45M  that could not have evolved through normal processes within the lifetime of our universe. Therefore, these objects can only be created through a common envelope phase or a stable Roche lobe overflow while in a binary (Pelisoli & …

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